Extraction and Preservation Protocol of Anti-Cancer Agents from Marine World
نویسندگان
چکیده
Marine source plays an important role in the form of pharmaceutical care and for the discovery of new molecular structures (i.e. targets). Marine organisms are a source of new therapeutics, especially for oncology, as a tremendous chemical diversity is found in marine bacteria, fungus, cyanobacteria, seaweeds, mangroves, microalgae and other halophytes. Several marine-derived compounds are currently extracted and synthesized by chemical processes for cancer treatment. By studying various papers related to marine source for new therapeutics for cancer treatment instead of other chemical enriched sources, the marine sources are largely unexplored for anticancer lead compounds. Hence this paper reviews results on the aspect with a view to provide basic information about the methods to produce extracts from marine organisms that are unique and different from that used by marine natural products chemists previously, yields both organic solvents and water soluble material for anti-cancer screening purpose. Chemists synthesize these compounds and their analogues in the laboratory for studying their activity towards various cancer cell lines.
منابع مشابه
Rapid DNA Extraction Protocol from Stool, Suitable for Molecular Genetic Diagnosis of Colon Cancer
Colorectal cancer (CRC) is one of the most common forms of cancers in the world and is curable if diagnosed at the early stage. Analysis of DNA extracted from stool specimens is a recent advantage to cancer diagnostics. Many protocols have been recommended for DNA extraction from stool, and almost allof them are difficult and time consuming, dealing with high amount of toxic materials like phen...
متن کاملPersian Gulf Bivalves: Bioactive Pharmaceutical Compounds and Biomedical Applications
Bivalves are a class of marine mollusks with high nutritional value in addition to various medicinal products. The Persian Gulf is home to 224 species from 29 families of bivalves identified so far. Based on research conducted in the Persian Gulf or other parts of the world, bioactive compounds exist in their shell and soft tissue. In this review article, we reviewed biomedical research related...
متن کاملMolecular docking and druggability studies of terpenoid-derived metabolites from marine sponges as IL-17A inhibitors
In this study, physicochemical properties of 49 compounds extracted from anti-inflammatory sponge species with the aim of ADMET test and Lipinski rule of five have been determined. Fourteen compounds, which showed best results, were subjected to molecular docking studies with IL-17. Among these compounds, Four compounds with low binding energy were obtained. These compounds, namely, frondosins ...
متن کاملA Review on Biosynthesis, Health Benefits and Extraction Methods of Fucoxanthin, Particular Marine Carotenoids in Algae
Fucoxanthin, an allenic carotenoid, is abundant in macro and microalgae as a component of the light-harvesting complex for photosynthesis and photo protection. This carotenoid has shown important pharmaceutical bioactivity, exerting antioxidant, anti-cancer, anti-diabetic, anti-obesity, anti-photoaging, anti-angiogenic, and anti-metastatic effects on a variety of biological models. This caroten...
متن کاملRapid Synthesis of Silver Nanoparticles by a Marine-derived Fungus Aspergillus Niger and their Antimicrobial Potentials
Recently, biosynthesis of nanoparticles has received attention due to an increasing need of developing rapid, simple and ecofriendly protocol. Pathogenicity of some of the organisms and lengthy reaction are the drawbacks involved with biosynthesis. We describe a simple protocol for rapid synthesis of silver nanoparticles through biological route using a marine-derived fungus Aspergillus niger. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012